HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: LIN41 (Q2Q1W2)
E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71)
Gene: TRIM71

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 494 Hs			1 868
+	Hs
		262171 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		TRIM3_HUMAN (178-868): 9.65e-167: 504: 29.11
+	Ce
		136810 UNC89_CAEEL (154-403): 1.77e-22: 103: 19.70		LIN41_CAEEL (112-868): 7.35e-135: 432: 31.82
+	Hs
		1029067 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		TRI56_HUMAN (111-868): 2.45e-106: 347: 16.86
+	Hs
		992753 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		TIF1B_HUMAN (195-490): 1.02e-84: 290: 25.25
+	Hs
		993702 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		TIF1B_HUMAN (195-490): 1.02e-84: 290: 25.25
+	Hs
		1028638 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		TIF1B_HUMAN (195-490): 1.02e-84: 290: 25.25
+	Hs
		992819 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		TRI67_HUMAN (50-571): 1.02e-71: 253: 16.47
+	Hs
		1028967 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		TRI67_HUMAN (50-571): 1.02e-71: 253: 16.47
+	Hs
		1028570 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		TRI67_HUMAN (50-571): 1.02e-71: 253: 16.47
+	Hs
		993746 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		TRI67_HUMAN (50-571): 1.02e-71: 253: 16.47
+	Hs
		1028705 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		TRI67_HUMAN (50-571): 1.02e-71: 253: 16.47
+	Hs
		1119142 PAP1L_HUMAN (1-189): 2.51e-32: 132: 16.50		TRI11_HUMAN (185-610): 8.84e-89: 291: 16.51
+	Hs
		516745 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		TRI33_HUMAN (91-507): 7.33e-73: 261: 17.73
+	Hs
		516566 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		TRI67_HUMAN (50-571): 1.02e-71: 253: 16.47
+	Hs
		1171683 PABP3_HUMAN (3-189): 1.09e-28: 121: 19.19		TRI67_HUMAN (50-571): 1.02e-71: 253: 16.47
+	Hs
		1031425 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		TRI11_HUMAN (185-610): 8.84e-89: 291: 16.51
+	Hs
		963511 TIAR_HUMAN (96-188): 2.66e-10: 63.8: 16.67		TIF1B_HUMAN (195-490): 1.02e-84: 290: 25.25
+	Hs
		1031370 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		TRI67_HUMAN (50-571): 1.02e-71: 253: 16.47
+	Hs
		1171430 RBM4B_HUMAN (3-104): 4.68e-11: 66.1: 23.08		TRI67_HUMAN (50-571): 1.02e-71: 253: 16.47
+	Hs
		963538 TIAR_HUMAN (96-188): 2.66e-10: 63.8: 16.67		TRI67_HUMAN (50-571): 1.02e-71: 253: 16.47