HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: CAND1 (Q86VP6)
Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (TBP-interacting protein of 120 kDa A) (TBP-interacting protein 120A) (p120 CAND1)
Gene: CAND1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 1230
+	Hs
		992833 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1028982 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1028575 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1028719 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		516581 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1031380 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		963543 TIAR_HUMAN (96-188): 2.66e-10: 63.8: 16.67		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		680463 TIA1_HUMAN (98-188): 6.06e-10: 63.1: 17.02		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		268701 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		SF3B1_HUMAN (365-1153): 1.41e-55: 214: 12.32
+	Hs
		268700 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		SF3B1_HUMAN (365-1153): 1.41e-55: 214: 12.32
+	Sc
		376762 PABP_YEAST (72-188): 2.61e-10: 64.6: 14.75		IMB2_YEAST (445-964): 4.58e-11: 69.5: 14.81