HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: DDX27 (Q96GQ7)
Probable ATP-dependent RNA helicase DDX27 (EC 3.6.4.13) (DEAD box protein 27)
Gene: DDX27

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 494 Hs			1 796
+	Hs
		992883 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		DDX27_HUMAN (1-796): 0: 545: 100.00
+	Hs
		1029037 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		DDX27_HUMAN (1-796): 0: 545: 100.00
+	Hs
		1028773 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		DDX27_HUMAN (1-796): 0: 545: 100.00
+	Sc
		699671 NOP4_YEAST (1-492): 1.19e-52: 190: 11.82		DRS1_YEAST (52-720): 4.7e-168: 505: 34.81
+	Hs
		757583 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		IF4A3_HUMAN (194-588): 2.69e-160: 473: 29.87
+	Hs
		757595 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		IF4A3_HUMAN (194-588): 2.69e-160: 473: 29.87
+	Hs
		757593 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		IF4A3_HUMAN (194-588): 2.69e-160: 473: 29.87
+	Hs
		757584 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		IF4A3_HUMAN (194-588): 2.69e-160: 473: 29.87
+	Hs
		757594 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		IF4A3_HUMAN (194-588): 2.69e-160: 473: 29.87
+	Hs
		516391 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		IF4A3_HUMAN (194-588): 2.69e-160: 473: 29.87
+	Hs
		133858 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		DDX3X_HUMAN (48-590): 2.07e-130: 405: 26.02
+	Mm
		936480 TIAR_MOUSE (3-105): 3.23e-13: 73.1: 19.05		DDX5_MOUSE (147-598): 5.39e-137: 420: 27.47
+	Hs
		1183350 RBM4B_HUMAN (3-104): 4.68e-11: 66.1: 23.08		DDX46_HUMAN (5-794): 3.5e-127: 407: 19.78
+	Hs
		134018 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		DDX3X_HUMAN (48-590): 2.07e-130: 405: 26.02
+	Sc
		742058 NOP4_YEAST (1-492): 1.19e-52: 190: 11.82		HAS1_YEAST (220-615): 9.18e-70: 240: 37.04
+	Hs
		992855 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		DDX54_HUMAN (191-571): 6.27e-60: 220: 40.21
+	Hs
		1029011 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		DDX54_HUMAN (191-571): 6.27e-60: 220: 40.21
+	Hs
		993778 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		DDX54_HUMAN (191-571): 6.27e-60: 220: 40.21
+	Hs
		1028747 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		DDX54_HUMAN (191-571): 6.27e-60: 220: 40.21
+	Dm
		447055 RBP1_DROME (3-68): 7.5e-19: 85: 40.58		VASA1_DROME (220-580): 5.8e-60: 217: 36.24