HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: PININ (Q9H307)
Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Desmosome-associated protein) (Domain-rich serine protein) (DRS protein) (DRSP) (Melanoma metastasis clone A protein) (Nuclear protein SDK3) (SR-like protein)
Gene: PNN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.636

Property	Details
Experiments	14578391, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 717
+	Hs
		1029089 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		PININ_HUMAN (1-717): 3.37e-144: 440: 100.00
+	Hs
		1031460 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		PININ_HUMAN (1-717): 3.37e-144: 440: 100.00
+	Dm
		644439 SRR55_DROME (3-175): 1.29e-46: 168: 63.64		Q8IFW3_DROME (5-308): 6.69e-61: 208: 27.30