HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30209976
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~zf-CCCH
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 1191
+	Hs
		992945 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1029104 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1028622 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		516698 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1329984 PABP3_HUMAN (3-189): 1.09e-28: 121: 19.19		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1031467 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		680490 TIA1_HUMAN (98-188): 6.06e-10: 63.1: 17.02		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		992807 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1028951 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1028567 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		993737 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		516550 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1136287 PABP3_HUMAN (3-189): 1.09e-28: 121: 19.19		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1031360 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		992772 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		MDC1_HUMAN (442-806): 1.14e-11: 71.8: 12.21
+	Hs
		1028547 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		MDC1_HUMAN (442-806): 1.14e-11: 71.8: 12.21
+	Hs
		516595 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		KMT2C_HUMAN (351-895): 4.49e-14: 79.7: 9.35
+	Hs
		963553 TIAR_HUMAN (96-188): 2.66e-10: 63.8: 16.67		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77