HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: PK1IP (Q9NWT1)
p21-activated protein kinase-interacting protein 1 (PAK/PLC-interacting protein 1) (hPIP1) (PAK1-interacting protein 1) (WD repeat-containing protein 84)
Gene: PAK1IP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 494 Hs			1 392
+	Hs
		992963 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		PK1IP_HUMAN (1-392): 6.72e-91: 280: 100.00
+	Hs
		1029131 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		PK1IP_HUMAN (1-392): 6.72e-91: 280: 100.00
+	Hs
		1028847 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		PK1IP_HUMAN (1-392): 6.72e-91: 280: 100.00
+	Sc
		594033 NOP4_YEAST (1-492): 1.19e-52: 190: 11.82		MAK11_YEAST (2-326): 1.84e-67: 221: 23.99
+	Hs
		992997 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		FBW1A_HUMAN (2-286): 6.86e-64: 216: 16.72
+	Hs
		1308788 RBM4B_HUMAN (3-104): 4.68e-11: 66.1: 23.08		PK1IP_HUMAN (1-392): 6.72e-91: 280: 100.00
+	Hs
		516754 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		FBW1A_HUMAN (2-286): 6.86e-64: 216: 16.72
+	Hs
		1028844 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		NLE1_HUMAN (154-389): 4e-38: 144: 10.04
+	Hs
		903165 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		WDR5_HUMAN (202-377): 2.11e-30: 120: 13.66
+	Hs
		992868 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		FBXW7_HUMAN (1-146): 6.23e-26: 111: 19.48
+	Hs
		1028587 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		FBXW7_HUMAN (1-146): 6.23e-26: 111: 19.48
+	Hs
		516733 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		FBW1B_HUMAN (3-231): 7.86e-44: 161: 16.87
+	Hs
		993788 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		FBXW7_HUMAN (1-146): 6.23e-26: 111: 19.48
+	Hs
		1031501 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		FBW1A_HUMAN (2-286): 6.86e-64: 216: 16.72
+	Hs
		1028761 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		FBXW7_HUMAN (1-146): 6.23e-26: 111: 19.48
+	Hs
		1029029 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		SNR40_HUMAN (237-391): 4.8e-13: 71.8: 9.62
+	Hs
		516438 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		WDR5_HUMAN (202-377): 2.11e-30: 120: 13.66
+	Hs
		1031492 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		FBW1B_HUMAN (3-231): 7.86e-44: 161: 16.87
+	Hs
		1308786 RBM4B_HUMAN (3-104): 4.68e-11: 66.1: 23.08		NLE1_HUMAN (154-389): 4e-38: 144: 10.04
+	Hs
		903196 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		WDR5_HUMAN (202-377): 2.11e-30: 120: 13.66