HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: TR150 (Q9Y2W1)
Thyroid hormone receptor-associated protein 3 (BCLAF1 and THRAP3 family member 2) (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150)
Gene: THRAP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006397 - mRNA processing GO:0008380 - RNA splicing and 1 others more... GO:0016607 - nuclear speck
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 955
+	Hs
		993001 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		TR150_HUMAN (1-955): 9.81e-127: 408: 100.00
+	Hs
		1029168 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		TR150_HUMAN (1-955): 9.81e-127: 408: 100.00
+	Hs
		1029137 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		1028627 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		1028977 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		RBBP6_HUMAN (20-841): 1.66e-72: 264: 13.81
+	Hs
		993755 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		RBBP6_HUMAN (20-841): 1.66e-72: 264: 13.81
+	Hs
		965152 PABP3_HUMAN (3-189): 1.09e-28: 121: 19.19		ANK2_HUMAN (47-877): 6.14e-50: 195: 12.46
+	Hs
		992995 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		1029163 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		993872 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		1028876 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		992772 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		MDC1_HUMAN (2-649): 1.14e-11: 71.2: 8.49
+	Hs
		1028547 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		MDC1_HUMAN (2-649): 1.14e-11: 71.2: 8.49
+	Hs
		516749 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		516609 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		TITIN_HUMAN (105-799): 3.29e-11: 70: 7.20
+	Ce
		136802 UNC89_CAEEL (154-403): 1.77e-22: 103: 19.70		UNC22_CAEEL (115-817): 2.1e-09: 63.9: 15.40
+	Hs
		1031405 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		TITIN_HUMAN (105-799): 3.29e-11: 70: 7.20