HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: RBM19 (Q9Y4C8)
Probable RNA-binding protein 19 (RNA-binding motif protein 19)
Gene: RBM19

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 494 Hs			1 960
+	Hs
		1029175 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		RBM19_HUMAN (1-960): 1.48e-162: 503: 100.00
+	Hs
		1028887 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		RBM19_HUMAN (1-960): 1.48e-162: 503: 100.00
+	Sc
		376750 NOP4_YEAST (1-492): 1.19e-52: 190: 11.82		PABP_YEAST (2-275): 3.67e-21: 101: 13.79
+	Hs
		516478 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		PABP1_HUMAN (3-272): 7.27e-19: 93.7: 11.85
+	Hs
		516493 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		PABP1_HUMAN (3-272): 7.27e-19: 93.7: 11.85
+	Hs
		992875 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		PABP5_HUMAN (3-119): 4.94e-14: 77.1: 19.66
+	Hs
		474020 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		PAB4L_HUMAN (3-80): 2.51e-16: 84.1: 25.64
+	Sc
		648366 NOP4_YEAST (1-492): 1.19e-52: 190: 11.82		NSR1_YEAST (719-894): 1.04e-12: 73.2: 29.78
+	Hs
		992743 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		ELAV2_HUMAN (732-894): 1.61e-11: 68.9: 28.83
+	Cn
		111495 J9VJ75_CRYNH (3-179): 9.05e-43: 161: 30.85		J9VUR9_CRYNH (2-275): 6.45e-20: 97.2: 9.66
+	Hs
		1028593 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		PABP5_HUMAN (3-119): 4.94e-14: 77.1: 19.66
+	Hs
		1028904 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		HNRPD_HUMAN (699-900): 4.2e-12: 70.9: 29.70
+	Hs
		1020247 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		ELAV2_HUMAN (732-894): 1.61e-11: 68.9: 28.83
+	Hs
		516495 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		PABP4_HUMAN (2-283): 1.29e-26: 118: 13.48
+	Hs
		516689 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		PABP3_HUMAN (3-305): 3e-25: 114: 14.19
+	Hs
		516339 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		PABP1_HUMAN (3-272): 7.27e-19: 93.7: 11.85
+	Hs
		1119141 PAP1L_HUMAN (1-189): 2.51e-32: 132: 16.50		PABP5_HUMAN (3-119): 4.94e-14: 77.1: 19.66
+	Hs
		516635 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		PABP5_HUMAN (3-119): 4.94e-14: 77.1: 19.66
+	Hs
		516511 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		HNRPD_HUMAN (699-900): 4.2e-12: 70.9: 29.70
+	Hs
		516484 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		ELAV2_HUMAN (732-894): 1.61e-11: 68.9: 28.83