HitPredict

Interactor 1: SMC5 (Q08204)
Structural maintenance of chromosomes protein 5
Gene: SMC5

Interactor 2: SMC6 (Q12749)
Structural maintenance of chromosomes protein 6 (DNA repair protein RHC18) (Rad18 homolog)
Gene: SMC6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 15738391, 25135640, 19141609, 33941673, 26299966, 29769404, 33301732, 37076626, 37968396, 14690591
Identification Methods affinity chromatography technology, two hybrid, biochemical, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_23~SMC_N
Common GO terms GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0003684 - damaged DNA binding
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
and 9 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1093
Sc

1 1114
+ Hs
+ Sp
+ Hs
+ Ce
+ Bs
+ Sp
+ Sp
+ Sp
+ Ce
+ Sc
+ Sc
+ Hs
+ Xl
+ Hs
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024