HitPredict

Interactor 1: PP2BA (Q08209)
Protein phosphatase 3 catalytic subunit alpha (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calcineurin A alpha) (Calmodulin-dependent calcineurin A subunit alpha isoform) (CNA alpha) (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform)
Gene: PPP3CA

Interactor 2: NFAC4 (Q14934)
Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T-cell transcription factor NFAT3) (NF-AT3)
Gene: NFATC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.667

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0033173 - calcineurin-NFAT signaling cascade
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0048813 - dendrite morphogenesis
GO:0050774 - negative regulation of dendrite morphogenesis
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 521
Hs

1 902
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Rn
+ Dm
+ Hs
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024