HitPredict

Interactor 1: PP2BA (Q08209)
Protein phosphatase 3 catalytic subunit alpha (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calcineurin A alpha) (Calmodulin-dependent calcineurin A subunit alpha isoform) (CNA alpha) (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform)
Gene: PPP3CA

Interactor 2: CANB2 (Q96LZ3)
Calcineurin subunit B type 2 (Calcineurin B-like protein) (CBLP) (Calcineurin BII) (CNBII) (PPP3R1-like) (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform)
Gene: PPP3R2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 32296183, 33961781
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_7~Metallophos
Common GO terms GO:0005509 - calcium ion binding
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0005955 - calcineurin complex
GO:0008287 - protein serine/threonine phosphatase complex
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 521
Hs

1 170
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+ Ce
+ Dm
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+ Sp
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024