HitPredict

Interactor 1: DHX9 (Q08211)
ATP-dependent RNA helicase A (EC 3.6.4.13) (DEAH box protein 9) (DExH-box helicase 9) (Leukophysin) (LKP) (Nuclear DNA helicase II) (NDH II) (RNA helicase A)
Gene: DHX9

Interactor 2: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000380 - alternative mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1270 Hs			1 344
+	Hs
		994318 DHX9_HUMAN (1-1241): 0: 1275: 100.00		RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05
+	Bt
		898864 DHX9_BOVIN (1-1169): 0: 1225: 94.78		PABP1_BOVIN (101-191): 1.28e-11: 67.6: 19.79
+	Hs
		992927 DHX36_HUMAN (258-1158): 0: 820: 32.70		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		992770 DHX8_HUMAN (51-1122): 0: 810: 20.54		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		1028815 DHX36_HUMAN (258-1158): 0: 820: 32.70		SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25
+	Hs
		1308767 DHX36_HUMAN (258-1158): 0: 820: 32.70		RBM4B_HUMAN (1-343): 2.62e-45: 160: 18.23
+	Hs
		1029088 DHX36_HUMAN (258-1158): 0: 820: 32.70		SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00
+	Hs
		993717 DHX8_HUMAN (51-1122): 0: 810: 20.54		SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47
+	Hs
		1028910 DHX8_HUMAN (51-1122): 0: 810: 20.54		SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00
+	Hs
		224784 DHX16_HUMAN (117-1103): 0: 806: 21.77		SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00
+	Hs
		992812 DHX57_HUMAN (99-1142): 0: 765: 28.74		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		993741 DHX57_HUMAN (99-1142): 0: 765: 28.74		SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47
+	Hs
		1028697 DHX57_HUMAN (99-1142): 0: 765: 28.74		SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25
+	Sc
		633969 PRP43_YEAST (320-1103): 0: 820: 26.18		GBP2_YEAST (4-203): 4.8e-23: 100: 19.05
+	Hs
		1028960 DHX57_HUMAN (99-1142): 0: 765: 28.74		SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00
+	Sc
		859409 PRP43_YEAST (320-1103): 0: 820: 26.18		NOP3_YEAST (3-326): 1.19e-19: 91.2: 19.94
+	Sc
		376861 PRP43_YEAST (320-1103): 0: 820: 26.18		PABP_YEAST (99-194): 1.33e-11: 67.6: 19.80
+	Hs
		1055487 DHX8_HUMAN (51-1122): 0: 810: 20.54		RBM28_HUMAN (4-248): 1.53e-12: 70.6: 14.61
+	Hs
		952120 DHX36_HUMAN (258-1158): 0: 820: 32.70		SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84
+	Hs
		952009 DHX30_HUMAN (381-1093): 3.3e-123: 412: 33.96		SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84