HitPredict

Interactor 1: DDR1 (Q08345)
Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)
Gene: DDR1

Interactor 2: RAD50 (Q92878)
DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)
Gene: RAD50

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21398698
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0046872 - metal ion binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 913 Hs			1 1312
+	Hs
		385286 NTRK1_HUMAN (607-902): 1.43e-66: 240: 45.27		RAD50_HUMAN (1-1312): 1.28e-115: 394: 100.00
+	Hs
		523231 SRC_HUMAN (361-912): 1.28e-125: 391: 23.60		MYH4_HUMAN (785-1235): 1.33e-14: 81.7: 12.88
+	Hs
		601523 FGFR2_HUMAN (583-905): 4.2e-109: 357: 34.05		GRDN_HUMAN (530-1217): 5.01e-21: 102: 12.32
+	Hs
		111443 J3QRU1_HUMAN (563-907): 1.44e-105: 339: 31.59		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		433272 YES_HUMAN (563-907): 1.25e-105: 339: 31.59		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		508036 FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52		GRDN_HUMAN (530-1217): 5.01e-21: 102: 12.32
+	Hs
		609288 FGFR3_HUMAN (551-905): 1.32e-110: 360: 32.16		SMC1A_HUMAN (290-1274): 4.82e-19: 95.7: 11.17
+	Hs
		609584 FGFR3_HUMAN (551-905): 1.32e-110: 360: 32.16		DAPLE_HUMAN (420-1089): 3.01e-18: 93.5: 13.59
+	Hs
		1083852 NTRK2_HUMAN (604-906): 1.75e-104: 345: 43.89		GRDN_HUMAN (530-1217): 5.01e-21: 102: 12.32
+	Hs
		384384 NTRK1_HUMAN (607-902): 1.43e-66: 240: 45.27		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		384941 NTRK1_HUMAN (607-902): 1.43e-66: 240: 45.27		GRDN_HUMAN (530-1217): 5.01e-21: 102: 12.32
+	Hs
		384844 NTRK1_HUMAN (607-902): 1.43e-66: 240: 45.27		SMC1A_HUMAN (290-1274): 4.82e-19: 95.7: 11.17
+	Hs
		384385 NTRK1_HUMAN (607-902): 1.43e-66: 240: 45.27		MYH10_HUMAN (44-596): 1.31e-16: 88.3: 13.20
+	Hs
		384210 NTRK1_HUMAN (607-902): 1.43e-66: 240: 45.27		DESP_HUMAN (190-1069): 1.96e-10: 67.8: 18.71
+	Hs
		411404 INSR_HUMAN (600-908): 7.71e-53: 202: 37.42		GRDN_HUMAN (530-1217): 5.01e-21: 102: 12.32
+	Hs
		384113 NTRK1_HUMAN (607-902): 1.43e-66: 240: 45.27		LAMB1_HUMAN (457-960): 2.73e-09: 63.9: 18.88