HitPredict - High confidence protein-protein interactions

Interactor 1: GATA4 (Q08369)
Transcription factor GATA-4 (GATA-binding factor 4)
Gene: GATA4

Interactor 2: SMAD2 (Q62432)
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (mMad2) (SMAD family member 2) (SMAD 2) (Smad2)
Gene: SMAD2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14662776
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001701 - in utero embryonic development GO:0001706 - endoderm formation and 16 others more... GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription GO:0007507 - heart development GO:0010628 - positive regulation of gene expression GO:0010629 - negative regulation of gene expression GO:0023019 - signal transduction involved in regulation of gene expression GO:0030513 - positive regulation of BMP signaling pathway GO:0045165 - cell fate commitment GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0048617 - embryonic foregut morphogenesis GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1	441
Mm

1	467

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Last updated: 15 Jul 2024