HitPredict

Interactor 1: F5GZ90 (F5GZ90)
Denticleless E3 ubiquitin protein ligase homolog
Gene: DTL

Interactor 2: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 688 Hs			1 913
+	Hs
		1043441 WDR5B_HUMAN (2-201): 6.69e-53: 187: 14.88		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		903209 WDR5_HUMAN (2-201): 9.91e-53: 186: 14.88		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		1043499 FBXW7_HUMAN (217-475): 6.64e-41: 161: 11.88		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		1043478 PHIP_HUMAN (162-446): 3.29e-37: 152: 12.06		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		245601 TBL1X_HUMAN (218-483): 4.34e-36: 145: 12.55		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		1016274 TBL3_HUMAN (1-126): 1.25e-30: 130: 23.81		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		1043621 DTL_HUMAN (7-261): 4.05e-30: 128: 11.36		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		1043085 WDR5B_HUMAN (2-201): 6.69e-53: 187: 14.88		CUL4A_HUMAN (161-913): 0: 955: 81.83
+	Hs
		903208 WDR5_HUMAN (2-201): 9.91e-53: 186: 14.88		CUL4A_HUMAN (161-913): 0: 955: 81.83
+	Hs
		1043124 PHIP_HUMAN (162-446): 3.29e-37: 152: 12.06		CUL4A_HUMAN (161-913): 0: 955: 81.83
+	Hs
		792982 LIS1_HUMAN (261-475): 1.54e-32: 132: 13.58		CUL4A_HUMAN (161-913): 0: 955: 81.83
+	Hs
		1043267 DTL_HUMAN (7-261): 4.05e-30: 128: 11.36		CUL4A_HUMAN (161-913): 0: 955: 81.83
+	Hs
		903207 WDR5_HUMAN (2-201): 9.91e-53: 186: 14.88		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		1042151 PHIP_HUMAN (162-446): 3.29e-37: 152: 12.06		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		1042699 DTL_HUMAN (7-261): 4.05e-30: 128: 11.36		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		903206 WDR5_HUMAN (2-201): 9.91e-53: 186: 14.88		CUL1_HUMAN (213-913): 0: 778: 30.16
+	Ce
		1088893 Q22059_CAEEL (20-522): 9.14e-75: 255: 22.61		CUL4_CAEEL (133-913): 0: 708: 32.21
+	Mm
		1257398 FBXW7_MOUSE (217-475): 4.22e-41: 162: 11.88		CUL1_MOUSE (213-913): 0: 778: 30.16
+	Hs
		1041133 FBXW7_HUMAN (217-475): 6.64e-41: 161: 11.88		CUL1_HUMAN (213-913): 0: 778: 30.16
+	Sp
		144469 CDT2_SCHPO (20-349): 1.38e-69: 237: 24.51		CUL4_SCHPO (191-912): 0: 659: 33.65