HitPredict

Interactor 1: GOGA2 (Q08379)
Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130) (GM130 autoantigen) (Golgin-95)
Gene: GOLGA2

Interactor 2: SHC3 (Q92529)
SHC-transforming protein 3 (Neuronal Shc) (N-Shc) (Protein Rai) (SHC-transforming protein C) (Src homology 2 domain-containing-transforming protein C3) (SH2 domain protein C3)
Gene: SHC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.523

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1002 Hs			1 594
+	Hs
		62377 GG6L9_HUMAN (385-497): 7.63e-13: 73.9: 45.13		SHC3_HUMAN (1-594): 0: 587: 100.00
+	Hs
		666019 MYH10_HUMAN (449-991): 1.35e-23: 110: 9.74		SHC1_HUMAN (3-593): 5.76e-176: 512: 46.65
+	Hs
		666018 MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87		SHC1_HUMAN (3-593): 5.76e-176: 512: 46.65
+	Hs
		666020 MYH11_HUMAN (664-1000): 6.52e-11: 69: 14.45		SHC1_HUMAN (3-593): 5.76e-176: 512: 46.65
+	Hs
		994916 GOGA2_HUMAN (1-1002): 2.79e-77: 275: 100.00		Q49AR9_HUMAN (11-496): 2.27e-59: 209: 13.08
+	Hs
		995097 GOGA2_HUMAN (1-1002): 2.79e-77: 275: 100.00		ANS1A_HUMAN (11-377): 5.8e-54: 200: 15.78
+	Hs
		523231 MYH4_HUMAN (421-973): 1.1e-20: 100: 12.27		SRC_HUMAN (361-594): 3.73e-49: 181: 18.18
+	Hs
		275589 MY18A_HUMAN (356-887): 3.84e-17: 89.4: 15.82		BCAR3_HUMAN (342-592): 6.06e-51: 190: 21.13
+	Hs
		412287 MY18A_HUMAN (356-887): 3.84e-17: 89.4: 15.82		FYN_HUMAN (438-585): 3.12e-44: 167: 20.76
+	Hs
		111443 MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87		J3QRU1_HUMAN (355-594): 1.49e-48: 179: 17.31
+	Hs
		433272 MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87		YES_HUMAN (355-594): 1.37e-48: 179: 17.31
+	Hs
		434048 DAPLE_HUMAN (329-961): 1.5e-14: 80.7: 13.08		LYN_HUMAN (404-594): 8.1e-44: 165: 20.69
+	Hs
		725134 MYH10_HUMAN (449-991): 1.35e-23: 110: 9.74		GRB2_HUMAN (445-594): 1.28e-34: 132: 22.08
+	Hs
		433795 GRDN_HUMAN (407-1001): 1.78e-12: 74: 10.63		LYN_HUMAN (404-594): 8.1e-44: 165: 20.69
+	Hs
		412058 MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87		FYN_HUMAN (438-585): 3.12e-44: 167: 20.76
+	Hs
		433620 MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87		LYN_HUMAN (404-594): 8.1e-44: 165: 20.69
+	Hs
		924736 MY18A_HUMAN (356-887): 3.84e-17: 89.4: 15.82		GRB2_HUMAN (445-594): 1.28e-34: 132: 22.08
+	Hs
		724756 MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87		GRB2_HUMAN (445-594): 1.28e-34: 132: 22.08
+	Hs
		728465 MYH11_HUMAN (664-1000): 6.52e-11: 69: 14.45		GRB2_HUMAN (445-594): 1.28e-34: 132: 22.08