HitPredict

Interactor 1: LG3BP (Q08380)
Galectin-3-binding protein (Basement membrane autoantigen p105) (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (MAC2BP) (Mac-2 BP) (Tumor-associated antigen 90K)
Gene: LGALS3BP

Interactor 2: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BACK~Cullin
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 585 Hs			1 776
+	Hs
		995361 LG3BP_HUMAN (1-585): 0: 646: 100.00		CUL4A_HUMAN (7-776): 0: 781: 30.41
+	Hs
		995362 LG3BP_HUMAN (1-585): 0: 646: 100.00		CUL4B_HUMAN (7-776): 0: 773: 29.90
+	Hs
		995360 LG3BP_HUMAN (1-585): 0: 646: 100.00		CUL3_HUMAN (9-776): 0: 748: 30.47
+	Hs
		995359 LG3BP_HUMAN (1-585): 0: 646: 100.00		CUL2_HUMAN (13-776): 0: 720: 35.98
+	Hs
		995409 LG3BP_HUMAN (1-585): 0: 646: 100.00		CUL5_HUMAN (2-776): 0: 622: 28.85
+	Hs
		1041022 KLH12_HUMAN (127-458): 1e-96: 308: 13.95		CUL1_HUMAN (1-776): 0: 911: 100.00
+	Rn
		70072 KLH17_RAT (135-456): 7.26e-90: 291: 14.68		B1WBY1_RAT (1-776): 0: 912: 99.87
+	Hs
		1043281 KLHL3_HUMAN (119-456): 1.3e-96: 308: 15.74		CUL4A_HUMAN (7-776): 0: 781: 30.41
+	Hs
		1043391 KLH12_HUMAN (127-458): 1e-96: 308: 13.95		CUL4B_HUMAN (7-776): 0: 773: 29.90
+	Hs
		1042881 KLH20_HUMAN (119-506): 4.11e-104: 328: 14.25		CUL3_HUMAN (9-776): 0: 748: 30.47
+	Hs
		1041712 KLH12_HUMAN (127-458): 1e-96: 308: 13.95		CUL3_HUMAN (9-776): 0: 748: 30.47
+	Hs
		1042768 KLHL3_HUMAN (119-456): 1.3e-96: 308: 15.74		CUL3_HUMAN (9-776): 0: 748: 30.47
+	Hs
		1042324 KLHL5_HUMAN (109-506): 2.43e-92: 301: 14.12		CUL3_HUMAN (9-776): 0: 748: 30.47
+	Hs
		1041853 KLH24_HUMAN (116-506): 3.86e-93: 299: 14.15		CUL3_HUMAN (9-776): 0: 748: 30.47
+	Mm
		1225041 KLHL2_MOUSE (107-456): 5.02e-92: 296: 12.39		CUL3_MOUSE (9-776): 0: 747: 30.35
+	Hs
		307170 KLHL2_HUMAN (107-456): 4.95e-91: 293: 12.39		CUL3_HUMAN (9-776): 0: 748: 30.47
+	Hs
		1041852 KLH17_HUMAN (135-456): 1.12e-89: 291: 15.29		CUL3_HUMAN (9-776): 0: 748: 30.47
+	Rn
		78189 KLH17_RAT (135-456): 7.26e-90: 291: 14.68		CUL3_RAT (9-776): 0: 748: 30.35
+	Hs
		299515 KLH18_HUMAN (116-439): 1.41e-89: 289: 14.89		CUL3_HUMAN (9-776): 0: 748: 30.47
+	Dm
		1213852 KLHDB_DROME (116-506): 7.51e-93: 299: 13.43		Q8IP45_DROME (10-776): 0: 729: 30.03