HitPredict

Interactor 1: GAGA (Q08605)
Transcription activator GAGA (Adh transcription factor 2) (GAGA factor) (GAF) (Neural conserved at 70F) (Trithorax-like protein)
Gene: Trl

Interactor 2: HDAC1 (Q94517)
Histone deacetylase HDAC1 (HD) (EC 3.5.1.98)
Gene: HDAC1

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23136390
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005700 - polytene chromosome GO:0006325 - chromatin organization GO:0031507 - heterochromatin formation GO:0045892 - negative regulation of DNA-templated transcription and 1 others more... GO:0048477 - oogenesis
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 581 Dm			1 521
+	Hs
		1038527 BCL6B_HUMAN (1-449): 1.01e-76: 253: 13.86		HDAC1_HUMAN (3-443): 0: 637: 81.18
+	Dm
		1213314 FRU_DROME (5-121): 2.28e-51: 191: 31.62		HDAC1_DROME (1-521): 0: 674: 100.00
+	Hs
		984006 ZBT16_HUMAN (1-341): 2.79e-49: 183: 17.50		HDAC2_HUMAN (2-488): 0: 659: 76.59
+	Mm
		140266 Q3UQ17_MOUSE (1-333): 2.3e-55: 200: 18.75		HDAC1_MOUSE (3-443): 0: 640: 81.18
+	Hs
		983971 ZBT16_HUMAN (1-341): 2.79e-49: 183: 17.50		HDAC1_HUMAN (3-443): 0: 637: 81.18
+	Hs
		1038377 ZN273_HUMAN (118-417): 3.55e-48: 178: 9.84		HDAC1_HUMAN (3-443): 0: 637: 81.18
+	Mm
		1257439 ZBT7C_MOUSE (1-412): 3.63e-72: 244: 10.94		Q9JM08_MOUSE (6-427): 0: 567: 56.13
+	Hs
		169690 ZBT7B_HUMAN (1-513): 1.53e-64: 222: 12.39		HDAC3_HUMAN (6-427): 0: 572: 56.37
+	Mm
		140211 ZBT7A_MOUSE (275-397): 3.59e-29: 123: 9.68		HDAC1_MOUSE (3-443): 0: 640: 81.18
+	Hs
		177270 ZBT16_HUMAN (1-341): 2.79e-49: 183: 17.50		HDAC3_HUMAN (6-427): 0: 572: 56.37
+	Hs
		312081 ZBT7A_HUMAN (395-539): 1.81e-11: 68.9: 7.84		HDAC2_HUMAN (2-488): 0: 659: 76.59
+	Mm
		936403 ZBT7B_MOUSE (382-495): 3.6e-10: 64.7: 2.56		HDAC2_MOUSE (2-488): 0: 655: 76.18
+	Hs
		312063 ZBT7A_HUMAN (395-539): 1.81e-11: 68.9: 7.84		HDAC1_HUMAN (3-443): 0: 637: 81.18
+	Mm
		140282 ZBT7B_MOUSE (382-495): 3.6e-10: 64.7: 2.56		HDAC1_MOUSE (3-443): 0: 640: 81.18
+	Hs
		177160 ZBT7A_HUMAN (395-539): 1.81e-11: 68.9: 7.84		HDAC3_HUMAN (6-427): 0: 572: 56.37
+	Mm
		292418 ZBT7B_MOUSE (382-495): 3.6e-10: 64.7: 2.56		HDAC3_MOUSE (6-427): 0: 573: 56.60
+	Hs
		169703 ZBT7B_HUMAN (1-513): 1.53e-64: 222: 12.39		HDAC4_HUMAN (5-405): 2.08e-133: 415: 22.86
+	Hs
		880692 ZBT16_HUMAN (1-341): 2.79e-49: 183: 17.50		HDAC4_HUMAN (5-405): 2.08e-133: 415: 22.86
+	Hs
		984038 ZBT16_HUMAN (1-341): 2.79e-49: 183: 17.50		HDAC6_HUMAN (9-323): 1.24e-99: 327: 23.55