Interactor 1: RPN8 (Q08723)
26S proteasome regulatory subunit RPN8
Gene: RPN8
Interactor 2: RPN5 (Q12250)
26S proteasome regulatory subunit RPN5 (Proteasome non-ATPase subunit 5)
Gene: RPN5
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.985 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11742986, 11805837, 11805826, 25919710, 15102831, 26451487, 16554755, 16429126, 16869714, 18467557, 37968396, 21289098, 22195964, 19446322 |
| Identification Methods | two hybrid, anti tag coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, biochemical, protein complementation assay, dihydrofolate reductase reconstruction |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | JAB~PCI, JAB~RPN5_C, MitMem_reg~PCI, MitMem_reg~RPN5_C |
| Common GO terms | GO:0000502 - proteasome complex GO:0008541 - proteasome regulatory particle, lid subcomplex GO:0034515 - proteasome storage granule GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
