HitPredict

Interactor 1: ISW2 (Q08773)
ISWI chromatin-remodeling complex ATPase ISW2 (EC 3.6.4.-) (Imitation switch protein 2)
Gene: ISW2

Interactor 2: H2AZ (Q12692)
Histone H2A.Z
Gene: HTZ1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	21179020
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1120 Sc			1 134
+	Sc
		392595 ISW2_YEAST (1-1120): 0: 1028: 100.00		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Hs
		229433 SMCA5_HUMAN (55-1089): 0: 954: 47.44		H2A2B_HUMAN (7-129): 3.24e-52: 162: 56.45
+	Hs
		229286 SMCA5_HUMAN (55-1089): 0: 954: 47.44		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		469951 SMCA1_HUMAN (73-1081): 0: 948: 47.89		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		229279 SMCA5_HUMAN (55-1089): 0: 954: 47.44		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Sc
		744936 ISW1_YEAST (1-1109): 0: 835: 48.59		H2AZ_YEAST (1-134): 2.81e-53: 165: 100.00
+	Sc
		392106 ISW1_YEAST (1-1109): 0: 835: 48.59		H2A1_YEAST (23-133): 7.94e-52: 162: 62.50
+	Sc
		392403 ISW1_YEAST (1-1109): 0: 835: 48.59		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Hs
		1018640 CHD3_HUMAN (25-1114): 0: 823: 26.91		H2A1H_HUMAN (7-133): 5.62e-52: 162: 55.47
+	Hs
		1059647 CHD4_HUMAN (31-1119): 0: 803: 27.38		H2A2C_HUMAN (7-134): 6.76e-52: 162: 55.04
+	Hs
		1059717 CHD4_HUMAN (31-1119): 0: 803: 27.38		H2A2B_HUMAN (7-129): 3.24e-52: 162: 56.45
+	Hs
		1059795 CHD4_HUMAN (31-1119): 0: 803: 27.38		H2A1H_HUMAN (7-133): 5.62e-52: 162: 55.47
+	Hs
		470021 CHD4_HUMAN (31-1119): 0: 803: 27.38		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		470170 CHD8_HUMAN (6-1093): 0: 799: 25.28		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Dm
		332757 CHDM_DROME (9-1118): 0: 770: 25.69		H2A_DROME (24-130): 7.69e-52: 161: 62.04
+	Hs
		391675 CHD3_HUMAN (25-1114): 0: 823: 26.91		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		391704 CHD4_HUMAN (31-1119): 0: 803: 27.38		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		391915 CHD8_HUMAN (6-1093): 0: 799: 25.28		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		391728 CHD9_HUMAN (5-1119): 0: 782: 25.55		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		151474 CHD2_HUMAN (19-1114): 0: 735: 27.62		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83