HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: TIF1B (Q13263)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: TRIM28

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29955894
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006281 - DNA repair
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 709 Hs			1 835
+	Hs
		996961 SSRP1_HUMAN (1-709): 0: 805: 100.00		TRI33_HUMAN (406-826): 1.6e-54: 206: 19.32
+	Hs
		170345 SSRP1_HUMAN (1-709): 0: 805: 100.00		TIF1A_HUMAN (404-808): 1.31e-52: 200: 21.55
+	Hs
		1029766 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Mm
		1142600 SOX17_MOUSE (475-709): 1.46e-33: 135: 12.97		TIF1B_MOUSE (57-835): 5.81e-159: 486: 94.87
+	Hs
		449709 HMGB1_HUMAN (543-634): 1e-14: 75.5: 34.04		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		175726 HM20B_HUMAN (508-709): 6.25e-36: 139: 18.81		TRI18_HUMAN (56-644): 5.73e-67: 237: 13.78
+	Hs
		668542 PMS1_HUMAN (400-704): 7.54e-34: 141: 16.23		PML_HUMAN (29-609): 1.21e-57: 214: 14.00
+	Hs
		1332331 SOX17_HUMAN (475-708): 1.45e-32: 132: 12.61		TRI33_HUMAN (406-826): 1.6e-54: 206: 19.32
+	Hs
		585039 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		RO52_HUMAN (104-502): 1.58e-48: 180: 12.94
+	Hs
		170476 SOX17_HUMAN (475-708): 1.45e-32: 132: 12.61		TIF1A_HUMAN (404-808): 1.31e-52: 200: 21.55
+	Hs
		170279 SOX5_HUMAN (441-648): 2.62e-30: 129: 19.23		TIF1A_HUMAN (404-808): 1.31e-52: 200: 21.55
+	Hs
		818613 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		TRI33_HUMAN (406-826): 1.6e-54: 206: 19.32
+	Hs
		617248 SP100_HUMAN (486-629): 1.52e-24: 111: 28.86		PML_HUMAN (29-609): 1.21e-57: 214: 14.00
+	Hs
		170296 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		TIF1A_HUMAN (404-808): 1.31e-52: 200: 21.55
+	Hs
		617392 SP100_HUMAN (486-629): 1.52e-24: 111: 28.86		TRI33_HUMAN (406-826): 1.6e-54: 206: 19.32
+	Hs
		818410 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		TRI56_HUMAN (47-532): 1.21e-51: 195: 17.68