HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: RBBP5 (Q15291)
Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)
Gene: RBBP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0042393 - histone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 709 Hs			1 538
+	Hs
		996930 SSRP1_HUMAN (1-709): 0: 805: 100.00		NLE1_HUMAN (2-135): 8.57e-34: 135: 18.38
+	Hs
		996824 SSRP1_HUMAN (1-709): 0: 805: 100.00		SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59
+	Hs
		996813 SSRP1_HUMAN (1-709): 0: 805: 100.00		FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56
+	Hs
		996721 SSRP1_HUMAN (1-709): 0: 805: 100.00		BRWD3_HUMAN (228-450): 4.8e-15: 80.8: 12.86
+	Hs
		996791 SSRP1_HUMAN (1-709): 0: 805: 100.00		PHIP_HUMAN (227-374): 6.69e-15: 80.4: 13.91
+	Hs
		903169 SSRP1_HUMAN (1-709): 0: 805: 100.00		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		818071 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00
+	Ce
		1089274 SOX2_CAEEL (503-706): 2.71e-35: 137: 15.46		WDR51_CAEEL (140-424): 4.13e-47: 170: 13.29
+	Hs
		1103013 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		SMU1_HUMAN (179-320): 3.28e-21: 99: 13.79
+	Hs
		1288324 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59
+	Hs
		1281404 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56
+	Hs
		869834 PMS1_HUMAN (400-704): 7.54e-34: 141: 16.23		SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59
+	Hs
		881823 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56
+	Hs
		818834 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56
+	Hs
		903450 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		817868 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		567746 UBF1_HUMAN (416-655): 2.71e-11: 69: 14.52		SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59
+	Hs
		567741 UBF1_HUMAN (416-655): 2.71e-11: 69: 14.52		FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56
+	Hs
		643290 HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		449632 HMGB1_HUMAN (543-634): 1e-14: 75.5: 34.04		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41