HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	29104064, 35271311, 37071682
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~Rtt106
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 709 Hs			1 136
+	Hs
		934695 SSRP1_HUMAN (1-709): 0: 805: 100.00		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		952293 SSRP1_HUMAN (1-709): 0: 805: 100.00		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Mm
		952739 SSRP1_MOUSE (1-709): 0: 805: 97.60		H33_MOUSE (1-136): 1.59e-61: 186: 97.06
+	Hs
		828208 SSRP1_HUMAN (1-709): 0: 805: 100.00		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Sp
		293581 POB3_SCHPO (2-491): 0: 588: 33.20		CENPA_SCHPO (26-133): 1.29e-42: 138: 62.71
+	Sc
		902054 POB3_YEAST (4-504): 0: 541: 29.66		H3_YEAST (1-136): 7.77e-56: 172: 88.97
+	Sc
		730916 POB3_YEAST (4-504): 0: 541: 29.66		CENPA_YEAST (18-134): 1.58e-41: 139: 56.67
+	Hs
		935263 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		935143 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		952640 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		952567 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		1157221 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		H3C_HUMAN (1-136): 8.83e-59: 179: 94.12
+	Hs
		869809 PMS1_HUMAN (400-704): 7.54e-34: 141: 16.23		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		818788 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		869810 PMS1_HUMAN (400-704): 7.54e-34: 141: 16.23		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		818791 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		727874 SOX6_HUMAN (449-700): 3.73e-33: 138: 14.96		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		828385 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Sc
		770100 RT106_YEAST (337-544): 3.23e-31: 129: 17.37		H3_YEAST (1-136): 7.77e-56: 172: 88.97
+	Hs
		617322 SP100_HUMAN (486-629): 1.52e-24: 111: 28.86		H32_HUMAN (1-136): 3.73e-61: 186: 100.00