HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~Rtt106
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0006337 - nucleosome disassembly and 1 others more... GO:0042393 - histone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 709 Hs			1 127
+	Hs
		420830 SSRP1_HUMAN (1-709): 0: 805: 100.00		H2B1J_HUMAN (1-127): 4.39e-54: 167: 85.04
+	Hs
		996694 SSRP1_HUMAN (1-709): 0: 805: 100.00		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		918316 SSRP1_HUMAN (1-709): 0: 805: 100.00		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		996812 SSRP1_HUMAN (1-709): 0: 805: 100.00		H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37
+	Hs
		996768 SSRP1_HUMAN (1-709): 0: 805: 100.00		H2B3B_HUMAN (1-127): 8.98e-51: 158: 85.83
+	Ce
		136643 SSP1B_CAEEL (1-695): 0: 648: 36.25		H2B1_CAEEL (8-127): 5.05e-50: 156: 78.33
+	Ce
		136714 SSP1B_CAEEL (1-695): 0: 648: 36.25		H2B4_CAEEL (23-127): 4.65e-49: 154: 86.67
+	Sc
		356009 POB3_YEAST (4-504): 0: 541: 29.66		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36
+	Hs
		1087421 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		707756 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		918706 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		241615 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25
+	Hs
		1282968 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		H2B1A_HUMAN (1-127): 1.72e-52: 163: 100.00
+	Hs
		297497 TOX4_HUMAN (484-678): 7.24e-32: 133: 23.86		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Sc
		355903 RT106_YEAST (337-544): 3.23e-31: 129: 17.37		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36
+	Sc
		355755 NHP6A_YEAST (530-619): 6.02e-28: 109: 35.56		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36
+	Sc
		355756 NHP6B_YEAST (520-619): 7.39e-28: 109: 34.00		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36
+	Hs
		643248 HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		643302 HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		643380 HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53		H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37