HitPredict

Interactor 1: NIP7 (Q08962)
60S ribosome subunit biogenesis protein NIP7 (Nuclear import protein 7)
Gene: NIP7

Interactor 2: MAK21 (Q12176)
Ribosome biogenesis protein MAK21 (Maintenance of killer protein 21) (Nucleolar complex protein 1)
Gene: MAK21

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	11805826, 16429126, 23209026
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor GO:0042273 - ribosomal large subunit biogenesis
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 181 Sc			1 1025
+	Hs
		1259539 NIP7_HUMAN (1-179): 2.41e-114: 323: 56.98		NOC3L_HUMAN (79-790): 2.08e-151: 471: 15.71
+	Sc
		987681 NIP7_YEAST (1-181): 3.56e-109: 310: 100.00		NOC4_YEAST (306-801): 1.18e-103: 337: 15.98
+	Sc
		992545 NIP7_YEAST (1-181): 3.56e-109: 310: 100.00		NOC3_YEAST (124-769): 2.85e-92: 310: 13.15