HitPredict

Interactor 1: VAC14 (Q08AM6)
Protein VAC14 homolog (Tax1-binding protein 2)
Gene: VAC14

Interactor 2: IF4A2 (Q14240)
Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)
Gene: EIF4A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 782 Hs			1 407
+	Dm
		972158 Q9VRV9_DROME (20-457): 1.96e-25: 114: 12.28		IF4A_DROME (14-407): 0: 510: 73.86
+	Sc
		485740 IMB4_YEAST (47-514): 2.93e-18: 92.2: 12.43		IF4A_YEAST (24-407): 7e-167: 474: 65.89
+	Hs
		892842 CAND1_HUMAN (4-541): 8.72e-15: 80.7: 11.74		IF4A1_HUMAN (3-407): 2.35e-159: 456: 89.88
+	Hs
		268601 SF3B1_HUMAN (8-584): 5.41e-31: 133: 9.71		DDX5_HUMAN (10-407): 3.86e-132: 394: 30.30
+	Hs
		268615 SF3B1_HUMAN (8-584): 5.41e-31: 133: 9.71		IF4A3_HUMAN (3-407): 2.28e-130: 382: 67.65
+	Hs
		1202027 CAND1_HUMAN (4-541): 8.72e-15: 80.7: 11.74		DDX17_HUMAN (25-407): 4.76e-131: 395: 31.20
+	Hs
		571509 CAND1_HUMAN (4-541): 8.72e-15: 80.7: 11.74		DDX5_HUMAN (10-407): 3.86e-132: 394: 30.30
+	Hs
		134112 CAND1_HUMAN (4-541): 8.72e-15: 80.7: 11.74		DDX3X_HUMAN (2-406): 3.77e-128: 385: 29.51
+	Hs
		757671 CAND1_HUMAN (4-541): 8.72e-15: 80.7: 11.74		IF4A3_HUMAN (3-407): 2.28e-130: 382: 67.65
+	Sc
		707858 GCN1_YEAST (5-656): 2.83e-18: 92.3: 12.03		DHH1_YEAST (33-403): 1.13e-98: 305: 43.67
+	Sc
		761949 IMB4_YEAST (47-514): 2.93e-18: 92.2: 12.43		DHH1_YEAST (33-403): 1.13e-98: 305: 43.67