Interactor 1: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Interactor 2: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.755

The method score is based on:

Property Details
Experiments 27705803, 9651585, 33961781, 37689310, 11602581, 9150133, 24981860, 12453419, 11118440, 21258344
Identification Methods affinity chromatography technology, pull down, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 7 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 425
Hs

1 1273
+ Hs
+ Hs
+ Sp
+ Hs
+ Hs
+ At
+ Dm
+ At
+ At
+ At

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Last updated: 15 Jul 2024