HitPredict

Interactor 1: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Interactor 2: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28977470
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CAF1C_H4-bd~WD40, WD40~WD40
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 342
+	Hs
		1083365 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		1083339 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		903171 RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		792949 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		LIS1_HUMAN (62-339): 9.49e-75: 238: 16.72
+	Hs
		245633 TBL1R_HUMAN (109-424): 2.86e-60: 205: 16.52		TBL1X_HUMAN (162-342): 3.97e-28: 116: 15.46
+	Hs
		903551 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		NLE1_HUMAN (114-333): 2.06e-53: 184: 18.05
+	Hs
		903349 WDR5B_HUMAN (92-417): 1.53e-68: 222: 18.54		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		725410 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		COPB2_HUMAN (54-331): 3.17e-47: 172: 18.38
+	Hs
		1309163 TBL1R_HUMAN (109-424): 2.86e-60: 205: 16.52		TBL1Y_HUMAN (207-337): 6.68e-19: 89.3: 14.38
+	Hs
		903418 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		1240442 POC1B_HUMAN (2-229): 2.56e-47: 170: 12.45		POC1A_HUMAN (201-341): 1.98e-27: 112: 18.31
+	Hs
		1074780 TAF5_HUMAN (153-417): 2.83e-46: 172: 15.23		TAF5_HUMAN (178-328): 1.2e-21: 98: 18.42
+	Hs
		245546 TBL1X_HUMAN (207-424): 3.72e-35: 138: 17.63		TBL1X_HUMAN (162-342): 3.97e-28: 116: 15.46
+	Hs
		245630 TBL1X_HUMAN (207-424): 3.72e-35: 138: 17.63		TBL1Y_HUMAN (207-337): 6.68e-19: 89.3: 14.38
+	Hs
		903077 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		196984 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		PRP4_HUMAN (253-341): 3.86e-10: 62.8: 13.40
+	Dm
		1358845 WDS_DROME (267-425): 9.83e-34: 131: 26.22		WDS_DROME (3-110): 6.27e-10: 61.6: 8.48