HitPredict

Interactor 1: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Interactor 2: BC11B (Q9C0K0)
B-cell lymphoma/leukemia 11B (BCL-11B) (B-cell CLL/lymphoma 11B) (COUP-TF-interacting protein 2) (Radiation-induced tumor suppressor gene 1 protein) (hRit1)
Gene: BCL11B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	33961781, 16091750
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0008285 - negative regulation of cell population proliferation
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 894
+	Hs
		997899 RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00		BC11A_HUMAN (1-889): 1.21e-165: 505: 49.02
+	Hs
		1083385 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		BC11A_HUMAN (1-889): 1.21e-165: 505: 49.02
+	Hs
		997826 RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00		ZN296_HUMAN (425-506): 1.24e-09: 63.5: 44.05
+	Hs
		1083379 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		BC11B_HUMAN (856-894): 9.88e-10: 64.4: 23.08
+	Hs
		1083325 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		ZN296_HUMAN (425-506): 1.24e-09: 63.5: 44.05
+	Mm
		925840 LIS1_MOUSE (313-422): 7.78e-17: 83.7: 16.36		ZN322_MOUSE (792-879): 1.92e-09: 62.8: 36.36