HitPredict

Interactor 1: F6M2J9 (F6M2J9)
Nuclear receptor coactivator-6 beta
Gene: Ncoa6

Interactor 2: F8WI37 (F8WI37)
[histone H3]-lysine(4) N-methyltransferase (EC 2.1.1.364)
Gene: Kmt2c

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17021013
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1077 Mm			1 4904
+	Mm
		1207212 NCOA6_MOUSE (161-1009): 1.27e-10: 68.3: 11.23		KMT2C_MOUSE (1-4904): 0: 2401: 99.98
+	Hs
		1057773 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		KMT2C_HUMAN (1-4904): 0: 2249: 84.59
+	Hs
		1056940 MDC1_HUMAN (437-1070): 2.63e-13: 76.8: 8.33		NSD1_HUMAN (3441-4903): 5.92e-102: 372: 11.55
+	Hs
		554310 MUC1_HUMAN (195-1060): 3.05e-42: 170: 10.23		EZH2_HUMAN (4584-4886): 5.87e-78: 278: 22.19
+	Hs
		1080263 MUC4_HUMAN (139-1071): 4.51e-20: 99.1: 8.40		EZH2_HUMAN (4584-4886): 5.87e-78: 278: 22.19
+	Hs
		1056830 MDC1_HUMAN (437-1070): 2.63e-13: 76.8: 8.33		CHD4_HUMAN (328-674): 3.91e-75: 283: 14.95
+	Hs
		1080420 CHD7_HUMAN (524-1066): 4.5e-12: 72.9: 12.83		EZH2_HUMAN (4584-4886): 5.87e-78: 278: 22.19
+	Hs
		1080127 KMT2C_HUMAN (426-997): 1.81e-10: 67.9: 8.92		EZH2_HUMAN (4584-4886): 5.87e-78: 278: 22.19
+	Dm
		1129083 Q9VLS7_DROME (121-890): 2.92e-11: 70.2: 8.40		SET1_DROME (4607-4904): 2.97e-62: 240: 27.52
+	Hs
		165699 KMT2C_HUMAN (426-997): 1.81e-10: 67.9: 8.92		SET1A_HUMAN (4631-4904): 1.42e-54: 215: 29.73
+	Hs
		331812 MDC1_HUMAN (437-1070): 2.63e-13: 76.8: 8.33		NSD2_HUMAN (4-439): 1.47e-46: 188: 16.33
+	Hs
		1303336 MUC4_HUMAN (139-1071): 4.51e-20: 99.1: 8.40		MUC4_HUMAN (1380-2605): 1.47e-34: 150: 11.21
+	Hs
		1057804 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		SET1B_HUMAN (4771-4904): 4.53e-24: 115: 51.11
+	Hs
		1057802 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		KMT2B_HUMAN (229-331): 5.25e-16: 88.6: 28.16
+	Hs
		1243852 KMT2C_HUMAN (426-997): 1.81e-10: 67.9: 8.92		KMT2B_HUMAN (229-331): 5.25e-16: 88.6: 28.16
+	Dm
		113976 M9PB30_DROME (387-1070): 9.52e-17: 88.3: 9.87		M9PB30_DROME (3388-4148): 7.98e-10: 68.1: 11.38
+	Hs
		975251 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		KMT2A_HUMAN (231-331): 3.07e-15: 85.9: 31.68
+	Hs
		975285 KMT2C_HUMAN (426-997): 1.81e-10: 67.9: 8.92		KMT2A_HUMAN (231-331): 3.07e-15: 85.9: 31.68
+	Hs
		152645 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		KMT2D_HUMAN (2992-3888): 5.12e-09: 65.4: 10.74
+	Hs
		152667 KMT2C_HUMAN (426-997): 1.81e-10: 67.9: 8.92		KMT2D_HUMAN (2992-3888): 5.12e-09: 65.4: 10.74