Interactor 1: ABCC8 (Q09428)
ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1)
Gene: ABCC8

Interactor 2: KCJ11 (Q14654)
ATP-sensitive inward rectifier potassium channel 11 (IKATP) (Inward rectifier K(+) channel Kir6.2) (Potassium channel, inwardly rectifying subfamily J member 11)
Gene: KCNJ11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.641

The method score is based on:

Property Details
Experiments 12941953, 19805355, 29286281
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, 3D electron microscopy
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0008282 - inward rectifying potassium channel
GO:0009410 - response to xenobiotic stimulus
GO:0015272 - ATP-activated inward rectifier potassium channel activity
and 6 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1581
Hs

1 390
+ Mm
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024