HitPredict

Interactor 1: F6M2J9 (F6M2J9)
Nuclear receptor coactivator-6 beta
Gene: Ncoa6

Interactor 2: ESR1 (P19785)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10681503
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005667 - transcription regulator complex GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1077 Mm			1 599
+	Mm
		99855 F6M2J9_MOUSE (1-1077): 2.8e-179: 554: 100.00		ESR2_MOUSE (27-582): 7.09e-129: 390: 44.62
+	Hs
		368927 MUC1_HUMAN (195-1060): 3.05e-42: 170: 10.23		ESR1_HUMAN (1-599): 0: 596: 88.98
+	Hs
		369607 MDC1_HUMAN (437-1070): 2.63e-13: 76.8: 8.33		ESR1_HUMAN (1-599): 0: 596: 88.98
+	Hs
		370607 CHD7_HUMAN (524-1066): 4.5e-12: 72.9: 12.83		ESR1_HUMAN (1-599): 0: 596: 88.98
+	Hs
		369612 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		ESR1_HUMAN (1-599): 0: 596: 88.98
+	Hs
		554348 MUC1_HUMAN (195-1060): 3.05e-42: 170: 10.23		ESR2_HUMAN (27-582): 8.84e-130: 392: 44.72
+	Hs
		1056909 MDC1_HUMAN (437-1070): 2.63e-13: 76.8: 8.33		ESR2_HUMAN (27-582): 8.84e-130: 392: 44.72
+	Hs
		867111 SC24C_HUMAN (475-791): 2.01e-12: 73.9: 13.79		ESR2_HUMAN (27-582): 8.84e-130: 392: 44.72
+	Hs
		1269810 CHD7_HUMAN (524-1066): 4.5e-12: 72.9: 12.83		ESR2_HUMAN (27-582): 8.84e-130: 392: 44.72
+	Hs
		1270066 PCLO_HUMAN (544-1069): 4.74e-11: 69.8: 9.47		ESR2_HUMAN (27-582): 8.84e-130: 392: 44.72
+	Hs
		782677 CHD7_HUMAN (524-1066): 4.5e-12: 72.9: 12.83		HNF4A_HUMAN (130-596): 3.28e-115: 353: 20.56
+	Mm
		93662 E9Q6A7_MOUSE (139-666): 4.05e-12: 72.9: 13.96		ERR2_MOUSE (95-551): 1.1e-114: 350: 33.04
+	Mm
		101828 F8WI37_MOUSE (404-1036): 1.22e-11: 71.8: 10.83		ERR2_MOUSE (95-551): 1.1e-114: 350: 33.04
+	Mm
		1142676 KMT2C_MOUSE (404-1036): 1.24e-11: 71.8: 10.83		ERR2_MOUSE (95-551): 1.1e-114: 350: 33.04
+	Hs
		377760 CHD7_HUMAN (524-1066): 4.5e-12: 72.9: 12.83		GCR_HUMAN (18-562): 2.77e-104: 334: 21.48
+	Hs
		231019 L37A3_HUMAN (196-729): 5.29e-12: 72.7: 14.61		GCR_HUMAN (18-562): 2.77e-104: 334: 21.48
+	Hs
		377327 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		GCR_HUMAN (18-562): 2.77e-104: 334: 21.48
+	Hs
		487431 MDC1_HUMAN (437-1070): 2.63e-13: 76.8: 8.33		ANDR_HUMAN (170-459): 5.22e-38: 152: 30.23
+	Hs
		487803 CHD7_HUMAN (524-1066): 4.5e-12: 72.9: 12.83		ANDR_HUMAN (170-459): 5.22e-38: 152: 30.23
+	Hs
		487433 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		ANDR_HUMAN (170-459): 5.22e-38: 152: 30.23