HitPredict

Interactor 1: F6M2J9 (F6M2J9)
Nuclear receptor coactivator-6 beta
Gene: Ncoa6

Interactor 2: PPARG (P37238)
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3)
Gene: PPARG

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10681503
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030374 - nuclear receptor coactivator activity GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1077 Mm			1 505
+	Mm
		99857 F6M2J9_MOUSE (1-1077): 2.8e-179: 554: 100.00		PPARA_MOUSE (57-505): 1.11e-119: 361: 54.41
+	Mm
		99856 F6M2J9_MOUSE (1-1077): 2.8e-179: 554: 100.00		ESR1_MOUSE (31-501): 1.59e-104: 326: 19.35
+	Mm
		99855 F6M2J9_MOUSE (1-1077): 2.8e-179: 554: 100.00		ESR2_MOUSE (10-502): 1.4e-98: 309: 19.35
+	Mm
		99859 F6M2J9_MOUSE (1-1077): 2.8e-179: 554: 100.00		THB_MOUSE (84-503): 9.6e-100: 309: 23.84
+	Hs
		554279 MUC1_HUMAN (195-1060): 3.05e-42: 170: 10.23		PPARG_HUMAN (1-505): 1.01e-174: 503: 96.04
+	Hs
		740524 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		PPARG_HUMAN (1-505): 1.01e-174: 503: 96.04
+	Hs
		368927 MUC1_HUMAN (195-1060): 3.05e-42: 170: 10.23		ESR1_HUMAN (38-501): 2.35e-107: 333: 19.26
+	Hs
		587169 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		RXRA_HUMAN (3-502): 4.1e-114: 346: 22.86
+	Hs
		369607 MDC1_HUMAN (437-1070): 2.63e-13: 76.8: 8.33		ESR1_HUMAN (38-501): 2.35e-107: 333: 19.26
+	Hs
		370607 CHD7_HUMAN (524-1066): 4.5e-12: 72.9: 12.83		ESR1_HUMAN (38-501): 2.35e-107: 333: 19.26
+	Hs
		369612 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		ESR1_HUMAN (38-501): 2.35e-107: 333: 19.26
+	Hs
		377760 CHD7_HUMAN (524-1066): 4.5e-12: 72.9: 12.83		GCR_HUMAN (2-503): 1.51e-101: 323: 18.47
+	Hs
		231019 L37A3_HUMAN (196-729): 5.29e-12: 72.7: 14.61		GCR_HUMAN (2-503): 1.51e-101: 323: 18.47
+	Mm
		57184 CHD7_MOUSE (147-525): 5.97e-16: 85.6: 11.50		THB_MOUSE (84-503): 9.6e-100: 309: 23.84
+	Hs
		487970 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		RARA_HUMAN (32-503): 2.97e-106: 326: 25.90
+	Hs
		377327 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		GCR_HUMAN (2-503): 1.51e-101: 323: 18.47
+	Hs
		782677 CHD7_HUMAN (524-1066): 4.5e-12: 72.9: 12.83		HNF4A_HUMAN (89-501): 7.67e-102: 315: 20.52
+	Hs
		265866 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		NR1I2_HUMAN (139-501): 1.78e-103: 318: 26.45
+	Hs
		500485 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		THB_HUMAN (84-503): 1.73e-98: 306: 23.61
+	Hs
		509950 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		VDR_HUMAN (120-504): 2.97e-95: 297: 24.23