HitPredict

Interactor 1: F6M2J9 (F6M2J9)
Nuclear receptor coactivator-6 beta
Gene: Ncoa6

Interactor 2: THB (P37242)
Thyroid hormone receptor beta (Nuclear receptor subfamily 1 group A member 2) (c-erbA-2) (c-erbA-beta)
Gene: Thrb

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	10681503, 34474245
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1077 Mm			1 461
+	Mm
		99857 F6M2J9_MOUSE (1-1077): 2.8e-179: 554: 100.00		PPARA_MOUSE (107-461): 6.12e-114: 344: 28.73
+	Mm
		99860 F6M2J9_MOUSE (1-1077): 2.8e-179: 554: 100.00		THA_MOUSE (88-430): 1.24e-107: 329: 78.72
+	Mm
		99855 F6M2J9_MOUSE (1-1077): 2.8e-179: 554: 100.00		ESR2_MOUSE (2-459): 3.53e-105: 324: 21.44
+	Mm
		99856 F6M2J9_MOUSE (1-1077): 2.8e-179: 554: 100.00		ESR1_MOUSE (1-460): 6.07e-103: 321: 19.42
+	Mm
		99858 F6M2J9_MOUSE (1-1077): 2.8e-179: 554: 100.00		PPARG_MOUSE (28-461): 3.39e-103: 318: 24.33
+	Mm
		57184 CHD7_MOUSE (147-525): 5.97e-16: 85.6: 11.50		THB_MOUSE (1-461): 1.59e-148: 433: 100.00
+	Hs
		368927 MUC1_HUMAN (195-1060): 3.05e-42: 170: 10.23		ESR1_HUMAN (16-460): 4.74e-106: 328: 19.40
+	Hs
		500485 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		THB_HUMAN (1-461): 6.66e-147: 428: 96.53
+	Hs
		554279 MUC1_HUMAN (195-1060): 3.05e-42: 170: 10.23		PPARG_HUMAN (28-461): 1.61e-103: 319: 24.55
+	Hs
		587169 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		RXRA_HUMAN (2-460): 1.91e-124: 371: 21.28
+	Hs
		487970 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		RARA_HUMAN (5-461): 5.98e-114: 344: 29.32
+	Hs
		369607 MDC1_HUMAN (437-1070): 2.63e-13: 76.8: 8.33		ESR1_HUMAN (16-460): 4.74e-106: 328: 19.40
+	Hs
		370607 CHD7_HUMAN (524-1066): 4.5e-12: 72.9: 12.83		ESR1_HUMAN (16-460): 4.74e-106: 328: 19.40
+	Hs
		500421 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		THA_HUMAN (88-430): 6.76e-108: 330: 78.72
+	Hs
		369612 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		ESR1_HUMAN (16-460): 4.74e-106: 328: 19.40
+	Hs
		782677 CHD7_HUMAN (524-1066): 4.5e-12: 72.9: 12.83		HNF4A_HUMAN (88-459): 3.09e-105: 322: 24.67
+	Mm
		93662 E9Q6A7_MOUSE (139-666): 4.05e-12: 72.9: 13.96		ERR2_MOUSE (7-460): 1.19e-104: 319: 22.47
+	Mm
		101828 F8WI37_MOUSE (404-1036): 1.22e-11: 71.8: 10.83		ERR2_MOUSE (7-460): 1.19e-104: 319: 22.47
+	Mm
		1142676 KMT2C_MOUSE (404-1036): 1.24e-11: 71.8: 10.83		ERR2_MOUSE (7-460): 1.19e-104: 319: 22.47
+	Hs
		265866 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		NR1I2_HUMAN (105-459): 1.18e-41: 155: 28.68