HitPredict

Interactor 1: F6M2J9 (F6M2J9)
Nuclear receptor coactivator-6 beta
Gene: Ncoa6

Interactor 2: THA (P63058)
Thyroid hormone receptor alpha (Nuclear receptor subfamily 1 group A member 1) (c-erbA-1) (c-erbA-alpha)
Gene: Thra

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10681503
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1077 Mm			1 492
+	Mm
		99856 F6M2J9_MOUSE (1-1077): 2.8e-179: 554: 100.00		ESR1_MOUSE (1-433): 1.56e-107: 334: 21.62
+	Mm
		99859 F6M2J9_MOUSE (1-1077): 2.8e-179: 554: 100.00		THB_MOUSE (22-407): 1.48e-107: 329: 70.47
+	Mm
		99858 F6M2J9_MOUSE (1-1077): 2.8e-179: 554: 100.00		PPARG_MOUSE (52-378): 5.02e-32: 130: 30.70
+	Hs
		500421 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		THA_HUMAN (1-492): 3.34e-156: 455: 95.73
+	Hs
		368927 MUC1_HUMAN (195-1060): 3.05e-42: 170: 10.23		ESR1_HUMAN (1-432): 2.72e-109: 338: 20.13
+	Hs
		587169 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		RXRA_HUMAN (3-408): 9.15e-115: 347: 24.09
+	Hs
		369607 MDC1_HUMAN (437-1070): 2.63e-13: 76.8: 8.33		ESR1_HUMAN (1-432): 2.72e-109: 338: 20.13
+	Mm
		57184 CHD7_MOUSE (147-525): 5.97e-16: 85.6: 11.50		THB_MOUSE (22-407): 1.48e-107: 329: 70.47
+	Hs
		370607 CHD7_HUMAN (524-1066): 4.5e-12: 72.9: 12.83		ESR1_HUMAN (1-432): 2.72e-109: 338: 20.13
+	Hs
		369612 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		ESR1_HUMAN (1-432): 2.72e-109: 338: 20.13
+	Hs
		782677 CHD7_HUMAN (524-1066): 4.5e-12: 72.9: 12.83		HNF4A_HUMAN (1-411): 4.88e-107: 328: 22.82
+	Hs
		500485 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		THB_HUMAN (22-407): 1.47e-107: 329: 71.24
+	Hs
		782542 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		HNF4A_HUMAN (1-411): 4.88e-107: 328: 22.82
+	Hs
		487970 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		RARA_HUMAN (7-407): 2.1e-104: 321: 31.17
+	Mm
		93662 E9Q6A7_MOUSE (139-666): 4.05e-12: 72.9: 13.96		ERR2_MOUSE (49-405): 1.63e-87: 277: 26.61
+	Mm
		101828 F8WI37_MOUSE (404-1036): 1.22e-11: 71.8: 10.83		ERR2_MOUSE (49-405): 1.63e-87: 277: 26.61
+	Mm
		1142676 KMT2C_MOUSE (404-1036): 1.24e-11: 71.8: 10.83		ERR2_MOUSE (49-405): 1.63e-87: 277: 26.61
+	Hs
		554279 MUC1_HUMAN (195-1060): 3.05e-42: 170: 10.23		PPARG_HUMAN (52-378): 1.29e-31: 129: 30.70
+	Hs
		265866 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		NR1I2_HUMAN (53-362): 2e-32: 130: 28.81
+	Hs
		740524 NCOA6_HUMAN (118-1046): 1.54e-10: 67.9: 10.25		PPARG_HUMAN (52-378): 1.29e-31: 129: 30.70