Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300
Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.98 | 1.00 | 0.991 |
The method score is based on:
Property | Details |
---|---|
Experiments | 19805293, 10545121, 10779504, 23934153, 10490106, 11689449, 15951563, 21791614, 23870121, 11433299, 15664194, 28844863, 29033323, 29746960, 10567538, 30110629, 32238831, 18815279, 10899165, 17065153 and 5 others
more... |
Identification Methods | enzymatic study, x-ray crystallography, affinity chromatography technology, pull down, anti tag coimmunoprecipitation |
Interaction Type | direct interaction, association, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Bromodomain~Bromodomain, Bromodomain~RING_CBP-p300, HAT_KAT11~HAT_KAT11, ZZ~ZZ |
Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000123 - histone acetyltransferase complex GO:0000785 - chromatin GO:0001221 - transcription coregulator binding GO:0001223 - transcription coactivator binding and 100 others more... |
Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024