HitPredict

Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33742100
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2414 Hs			1 551
+	Hs
		846760 EP300_HUMAN (1-2414): 0: 1113: 100.00		SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93
+	Hs
		998885 EP300_HUMAN (1-2414): 0: 1113: 100.00		CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82
+	Hs
		846947 EP300_HUMAN (1-2414): 0: 1113: 100.00		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		998651 EP300_HUMAN (1-2414): 0: 1113: 100.00		PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51
+	Hs
		516480 EP300_HUMAN (1-2414): 0: 1113: 100.00		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Dm
		115984 M9PH39_DROME (430-2323): 0: 769: 36.52		BRM_DROME (249-551): 1.19e-45: 175: 20.72
+	Hs
		1084666 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00
+	Hs
		846881 BAZ1A_HUMAN (889-1176): 3.58e-51: 202: 21.31		SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93
+	Hs
		846897 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93
+	Hs
		847093 BRWD1_HUMAN (1007-1168): 2.52e-44: 180: 32.93		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		847115 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		846993 BRDT_HUMAN (1036-1159): 2.03e-33: 143: 29.84		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		631379 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93
+	Hs
		846778 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93
+	Hs
		631380 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		846977 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		516745 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		847103 CHD7_HUMAN (69-452): 4.51e-13: 77.9: 12.02		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Mm
		1351630 PCLO_MOUSE (1988-2414): 9.66e-13: 76.7: 11.24		PCLO_MOUSE (195-468): 6.01e-14: 77.6: 11.31
+	Dm
		113976 M9PB30_DROME (5-444): 3.69e-13: 78.3: 7.05		M9PB30_DROME (190-412): 1.36e-12: 73: 16.67