HitPredict

Interactor 1: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Interactor 2: F8VQE9 (F8VQE9)
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
Gene: Agap3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RasGAP
Common GO terms	GO:0005096 - GTPase activator activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1340 Mm			1 910
+	Mm
		100045 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		AGAP1_MOUSE (59-895): 0: 773: 70.89
+	Mm
		93411 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		E9Q3K3_MOUSE (63-895): 0: 682: 62.61
+	Mm
		99969 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		AGAP2_MOUSE (3-879): 0: 607: 45.36
+	Hs
		1355995 NGAP_HUMAN (84-1338): 0: 800: 43.48		AGAP1_HUMAN (59-890): 0: 773: 71.43
+	Mm
		1012208 Q0VAV5_MOUSE (17-1338): 0: 890: 43.23		AGAP2_MOUSE (3-879): 0: 607: 45.36
+	Mm
		93233 E9PW37_MOUSE (17-1338): 0: 887: 43.30		AGAP2_MOUSE (3-879): 0: 607: 45.36
+	Mm
		1112542 DAB2P_MOUSE (97-1339): 0: 850: 47.79		AGAP2_MOUSE (3-879): 0: 607: 45.36
+	Mm
		88329 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		D3YX85_MOUSE (423-908): 1.71e-86: 299: 21.89
+	Mm
		100015 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		ASAP2_MOUSE (423-908): 6.74e-85: 294: 22.16
+	Mm
		100001 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		GIT1_MOUSE (668-875): 9.01e-77: 268: 34.69
+	Mm
		99942 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		RAB1A_MOUSE (116-329): 1.4e-81: 263: 21.27
+	Hs
		918932 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		RAB1A_HUMAN (116-329): 1.4e-81: 263: 21.27
+	Hs
		598546 NF1_HUMAN (408-712): 2.96e-82: 301: 23.21		AGAP1_HUMAN (59-890): 0: 773: 71.43
+	Mm
		1112670 RASL1_MOUSE (162-688): 1.39e-121: 399: 19.26		AGAP2_MOUSE (3-879): 0: 607: 45.36
+	Mm
		1112565 IQGA2_MOUSE (216-731): 3.33e-115: 398: 14.09		AGAP2_MOUSE (3-879): 0: 607: 45.36
+	Mm
		1112651 IQGA1_MOUSE (219-731): 1.36e-107: 377: 13.95		AGAP2_MOUSE (3-879): 0: 607: 45.36
+	Mm
		980214 NF1_MOUSE (408-712): 3.83e-82: 300: 23.51		AGAP2_MOUSE (3-879): 0: 607: 45.36
+	Mm
		99872 F6QQP6_MOUSE (942-1316): 8.91e-32: 135: 19.75		AGAP2_MOUSE (3-879): 0: 607: 45.36
+	Hs
		596403 RASA1_HUMAN (184-715): 9.24e-130: 428: 23.82		ACAP2_HUMAN (366-909): 3.23e-91: 307: 13.54