HitPredict

Interactor 1: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Interactor 2: MTAP2 (P20357)
Microtubule-associated protein 2 (MAP-2)
Gene: Map2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007409 - axonogenesis GO:0014069 - postsynaptic density GO:0016358 - dendrite development GO:0019901 - protein kinase binding GO:0043198 - dendritic shaft and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1340 Mm			1 1828
+	Hs
		503300 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		MTAP2_HUMAN (1-1828): 0: 601: 79.12
+	Hs
		807807 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		MAP1B_HUMAN (51-1813): 3.81e-100: 361: 9.85
+	Hs
		654034 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		MAP4_HUMAN (741-1795): 2.56e-65: 245: 16.65
+	Mm
		99899 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		TAU_MOUSE (1128-1828): 9.81e-61: 225: 23.37
+	Mm
		99916 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		MAP4_MOUSE (891-1796): 1.71e-58: 224: 17.14
+	Hs
		965139 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		ANK2_HUMAN (268-1529): 1.36e-16: 88.7: 10.31
+	Mm
		99903 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		MAP1B_MOUSE (1-1092): 1.2e-11: 72.6: 10.22
+	Mm
		100050 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		ANK2_MOUSE (123-1550): 1.37e-11: 72.5: 13.29
+	Hs
		807625 IQGA1_HUMAN (219-723): 6.44e-107: 374: 13.97		MAP1B_HUMAN (51-1813): 3.81e-100: 361: 9.85
+	Hs
		809486 IQGA1_HUMAN (219-723): 6.44e-107: 374: 13.97		SRRM2_HUMAN (9-1803): 7.23e-30: 132: 8.81