HitPredict

Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: ELF5 (Q9UKW6)
ETS-related transcription factor Elf-5 (E74-like factor 5) (Epithelium-restricted ESE-1-related Ets factor) (Epithelium-specific Ets transcription factor 2) (ESE-2)
Gene: ELF5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	33742100
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2414 Hs			1 265
+	Hs
		987759 EP300_HUMAN (1-2414): 0: 1113: 100.00		GABPA_HUMAN (4-265): 1.45e-75: 238: 22.68
+	Mm
		70891 EP300_MOUSE (1-2414): 0: 1090: 93.01		SPI1_MOUSE (11-259): 2.87e-52: 173: 22.10
+	Hs
		794535 EP300_HUMAN (1-2414): 0: 1113: 100.00		ETV4_HUMAN (112-260): 1.52e-40: 147: 24.50
+	Hs
		840433 EP300_HUMAN (1-2414): 0: 1113: 100.00		ETV1_HUMAN (117-260): 3.14e-40: 146: 29.05
+	Hs
		781139 EP300_HUMAN (1-2414): 0: 1113: 100.00		ETV5_HUMAN (128-257): 1.09e-39: 145: 29.10
+	Hs
		999010 EP300_HUMAN (1-2414): 0: 1113: 100.00		FEV_HUMAN (155-255): 1.2e-41: 144: 32.35
+	Hs
		542741 EP300_HUMAN (1-2414): 0: 1113: 100.00		ETS2_HUMAN (1-173): 3.97e-39: 143: 17.03
+	Hs
		584244 EP300_HUMAN (1-2414): 0: 1113: 100.00		ELK1_HUMAN (172-257): 7.84e-39: 141: 42.53
+	Mm
		70899 EP300_MOUSE (1-2414): 0: 1090: 93.01		ETV4_MOUSE (112-260): 1.22e-39: 145: 24.50
+	Hs
		507409 EP300_HUMAN (1-2414): 0: 1113: 100.00		ERG_HUMAN (36-141): 5.06e-27: 110: 23.36
+	Hs
		542006 EP300_HUMAN (1-2414): 0: 1113: 100.00		ETS1_HUMAN (22-167): 3.12e-27: 110: 17.69
+	Hs
		944608 EP300_HUMAN (1-2414): 0: 1113: 100.00		ELF3_HUMAN (15-192): 3.28e-26: 107: 14.61
+	Hs
		1304911 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		ELF4_HUMAN (1-264): 3.88e-68: 224: 21.17
+	Hs
		794578 NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89		ETV4_HUMAN (112-260): 1.52e-40: 147: 24.50
+	Hs
		840443 NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89		ETV1_HUMAN (117-260): 3.14e-40: 146: 29.05
+	Hs
		1304733 NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89		FEV_HUMAN (155-255): 1.2e-41: 144: 32.35
+	Hs
		542769 NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89		ETS2_HUMAN (1-173): 3.97e-39: 143: 17.03
+	Hs
		507535 NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89		ERG_HUMAN (36-141): 5.06e-27: 110: 23.36
+	Hs
		542091 NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89		ETS1_HUMAN (22-167): 3.12e-27: 110: 17.69
+	Hs
		507528 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		ERG_HUMAN (36-141): 5.06e-27: 110: 23.36