HitPredict

Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: TPX2 (Q9ULW0)
Targeting protein for Xklp2 (Differentially expressed in cancerous and non-cancerous lung cells 2) (DIL-2) (Hepatocellular carcinoma-associated antigen 519) (Hepatocellular carcinoma-associated antigen 90) (Protein fls353) (Restricted expression proliferation-associated protein 100) (p100)
Gene: TPX2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33742100
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006915 - apoptotic process
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2414 Hs			1 747
+	Hs
		1067191 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		TPX2_HUMAN (1-747): 2.4e-154: 468: 100.00
+	Hs
		1017366 BPTF_HUMAN (2011-2413): 1.11e-14: 82.9: 12.86		TPX2_HUMAN (1-747): 2.4e-154: 468: 100.00
+	Hs
		1057024 MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82		TPX2_HUMAN (1-747): 2.4e-154: 468: 100.00
+	Dm
		113976 M9PB30_DROME (5-444): 3.69e-13: 78.3: 7.05		M9PB30_DROME (191-729): 3.7e-14: 79.1: 8.07
+	Hs
		297832 BRWD3_HUMAN (1006-1157): 1.89e-10: 68.9: 27.93		K0754_HUMAN (181-739): 3.11e-12: 72.6: 12.02