HitPredict

Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30110629, 33742100
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2414 Hs			1 2752
+	Hs
		998981 EP300_HUMAN (1-2414): 0: 1113: 100.00		ZN469_HUMAN (653-2751): 4.46e-42: 173: 9.28
+	Hs
		311805 EP300_HUMAN (1-2414): 0: 1113: 100.00		TACC2_HUMAN (1893-2744): 4.03e-13: 78.2: 8.34
+	Hs
		1067200 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		1262846 PHIP_HUMAN (1068-1157): 6.78e-12: 73.6: 42.86		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		1164809 NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89		ANR11_HUMAN (430-2752): 2.96e-75: 283: 9.67
+	Hs
		1300957 BAZ1A_HUMAN (889-1176): 3.58e-51: 202: 21.31		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		164388 TRI66_HUMAN (268-1197): 1.08e-40: 168: 12.26		PRC2B_HUMAN (640-2750): 5.74e-64: 245: 9.36
+	Hs
		807791 CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25		MAP1B_HUMAN (15-1517): 8.71e-69: 261: 10.13
+	Hs
		1300971 CHD7_HUMAN (69-452): 4.51e-13: 77.9: 12.02		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		1164182 BRWD3_HUMAN (1006-1157): 1.89e-10: 68.9: 27.93		ZN469_HUMAN (653-2751): 4.46e-42: 173: 9.28
+	Hs
		1067006 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		NIPBL_HUMAN (333-1474): 1.68e-16: 89.1: 14.39
+	Hs
		1056897 MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82		BD1L1_HUMAN (16-2752): 1.77e-19: 99.2: 9.13
+	Mm
		1351630 PCLO_MOUSE (1988-2414): 9.66e-13: 76.7: 11.24		PCLO_MOUSE (8-2704): 3.33e-19: 98.2: 7.94
+	Hs
		1243827 KMT2C_HUMAN (416-1078): 1.02e-10: 70.1: 11.13		BD1L1_HUMAN (16-2752): 1.77e-19: 99.2: 9.13
+	Dm
		113976 M9PB30_DROME (5-444): 3.69e-13: 78.3: 7.05		M9PB30_DROME (2292-2752): 2.57e-14: 82: 11.45
+	Hs
		311825 CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25		TACC2_HUMAN (1893-2744): 4.03e-13: 78.2: 8.34
+	Hs
		297832 BRWD3_HUMAN (1006-1157): 1.89e-10: 68.9: 27.93		K0754_HUMAN (864-1413): 2.27e-10: 69.1: 16.44
+	Hs
		152667 KMT2C_HUMAN (416-1078): 1.02e-10: 70.1: 11.13		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Hs
		152675 CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75