Interactor 1: T23O (Q09474)
Tryptophan 2,3-dioxygenase (TDO) (EC 1.13.11.11) (Tryptamin 2,3-dioxygenase) (Tryptophan oxygenase) (TO) (TRPO) (Tryptophan pyrrolase) (Tryptophanase)
Gene: tdo-2

Interactor 2: T23O (Q09474)
Tryptophan 2,3-dioxygenase (TDO) (EC 1.13.11.11) (Tryptamin 2,3-dioxygenase) (Tryptophan oxygenase) (TO) (TRPO) (Tryptophan pyrrolase) (Tryptophanase)
Gene: tdo-2

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 14704431
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Trp_dioxygenase~Trp_dioxygenase
Common GO terms GO:0004833 - tryptophan 2,3-dioxygenase activity
GO:0019441 - tryptophan catabolic process to kynurenine
GO:0019442 - tryptophan catabolic process to acetyl-CoA
GO:0020037 - heme binding
GO:0046872 - metal ion binding
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 403
Ce

1 403
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024