HitPredict

Interactor 1: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Interactor 2: 1433E (P62259)
14-3-3 protein epsilon (14-3-3E)
Gene: Ywhae

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	27507650, 28706196, 28671696, 36417873
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0045202 - synapse GO:0098978 - glutamatergic synapse
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1340 Mm			1 255
+	Hs
		909931 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909664 DAB2P_HUMAN (97-1339): 0: 859: 47.63		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		910133 NGAP_HUMAN (84-1338): 0: 800: 43.48		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909576 GAPD1_HUMAN (412-1068): 2.04e-130: 439: 13.36		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909774 RASL3_HUMAN (169-868): 1.56e-117: 394: 34.68		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		598455 NF1_HUMAN (408-712): 2.96e-82: 301: 23.21		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Mm
		910233 NF1_MOUSE (408-712): 3.83e-82: 300: 23.51		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00