HitPredict

Interactor 1: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Interactor 2: NMDE2 (Q01097)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B)
Gene: Grin2b

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.84 0.60 0.714

The method score is based on:

Property Details
Experiments 27507650, 28706196, 28671696, 36417873, 10862698
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0014069 - postsynaptic density
GO:0016020 - membrane
GO:0043113 - receptor clustering
GO:0043408 - regulation of MAPK cascade
and 5 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1340
Mm

1 1482
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ Rn
+ Rn
+ Mm

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Last updated: 15 Jul 2024