HitPredict

Interactor 1: PSA3 (Q09682)
Probable proteasome subunit alpha type-3
Gene: SPAC13C5.01c

Interactor 2: PSA4 (Q10329)
Probable proteasome subunit alpha type-4
Gene: pre6

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	20133687, 24938783
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N, Proteasome_A_N~Proteasome_A_N
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0019773 - proteasome core complex, alpha-subunit complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 248 Sp			1 259
+	Ss
		94582 F2Z5L7_PIG (1-248): 6.52e-102: 298: 31.62		F1SBA5_PIG (2-226): 1.12e-97: 287: 55.51
+	Hs
		156223 PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62		PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59
+	Hs
		637315 PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62		PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27
+	Hs
		637325 PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62		PSA5_HUMAN (2-232): 7.74e-94: 277: 34.03
+	Hs
		637494 PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62		PSMA8_HUMAN (2-230): 1.66e-93: 277: 52.74
+	Ss
		94704 F2Z5L7_PIG (1-248): 6.52e-102: 298: 31.62		F2Z5K2_PIG (2-232): 7.74e-94: 277: 34.03
+	Hs
		156226 PSA4_HUMAN (1-238): 7.96e-98: 288: 53.56		PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59
+	Hs
		637318 PSA4_HUMAN (1-238): 7.96e-98: 288: 53.56		PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27
+	Hs
		637376 PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62		PSA6_HUMAN (2-236): 7.16e-90: 267: 29.88
+	Hs
		638067 PSA4_HUMAN (1-238): 7.96e-98: 288: 53.56		PSA5_HUMAN (2-232): 7.74e-94: 277: 34.03
+	Hs
		156169 PSA7_HUMAN (4-239): 1.01e-94: 279: 37.40		PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59
+	Ce
		1278563 PSA4_CAEEL (1-238): 1.84e-95: 281: 53.78		PSA7_CAEEL (1-232): 3.6e-93: 276: 50.21
+	Sc
		619364 PSA3_YEAST (2-246): 6.65e-95: 280: 61.22		PSA4_YEAST (1-232): 5.22e-93: 275: 58.48
+	Hs
		638100 PSA4_HUMAN (1-238): 7.96e-98: 288: 53.56		PSA6_HUMAN (2-236): 7.16e-90: 267: 29.88
+	Sc
		619338 PSA3_YEAST (2-246): 6.65e-95: 280: 61.22		PSA5_YEAST (2-245): 1.62e-91: 272: 32.54
+	Sp
		293714 PSA3_SCHPO (1-248): 1.18e-104: 304: 100.00		PSA2_SCHPO (4-211): 2.04e-44: 151: 37.44
+	Hs
		637316 PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62		PSA2_HUMAN (3-210): 2.47e-45: 153: 38.10
+	Hs
		637626 PSA4_HUMAN (1-238): 7.96e-98: 288: 53.56		PSA2_HUMAN (3-210): 2.47e-45: 153: 38.10