Interactor 1: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Interactor 2: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.694

The method score is based on:

Property Details
Experiments 27507650, 28671696, 28706196, 36417873
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0014069 - postsynaptic density
GO:0017124 - SH3 domain binding
GO:0048167 - regulation of synaptic plasticity
GO:0050804 - modulation of chemical synaptic transmission
and 2 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1340
Mm

1 1730
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Last updated: 15 Jul 2024