Interactor 1: PLXA1 (P70206)
Plexin-A1 (Plex 1) (Plexin-1)
Gene: Plxna1

Interactor 2: TREM2 (Q99NH8)
Triggering receptor expressed on myeloid cells 2 (TREM-2) (Triggering receptor expressed on monocytes 2)
Gene: TREM2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 0.90 0.656

The method score is based on:

Property Details
Experiments 22522930
Identification Methods anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Sema~V-set, TIG~V-set
Common GO terms GO:0002291 - T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
GO:0005886 - plasma membrane
GO:0017154 - semaphorin receptor activity
GO:0071526 - semaphorin-plexin signaling pathway
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 11Aug2025