HitPredict

Interactor 1: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Interactor 2: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.84 0.60 0.714

The method score is based on:

Property Details
Experiments 28706196, 28671696, 36417873, 27507650, 36604605
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0014069 - postsynaptic density
GO:0016020 - membrane
GO:0019901 - protein kinase binding
GO:0045202 - synapse
and 2 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1340
Mm

1 724
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Last updated: 15 Jul 2024