HitPredict

Interactor 1: SNX3 (O60493)
Sorting nexin-3 (Protein SDP3)
Gene: SNX3

Interactor 2: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0010976 - positive regulation of neuron projection development GO:0042177 - negative regulation of protein catabolic process
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 162 Hs			1 537
+	Hs
		412408 SNX12_HUMAN (5-161): 8.43e-52: 164: 80.26		FYN_HUMAN (1-537): 0: 643: 100.00
+	Hs
		234894 SNX3_HUMAN (1-162): 5.77e-58: 179: 100.00		SRC_HUMAN (1-537): 0: 598: 68.21
+	Hs
		523230 SNX9_HUMAN (1-145): 4.92e-32: 121: 20.53		SRC_HUMAN (1-537): 0: 598: 68.21
+	Hs
		433518 SNX9_HUMAN (1-145): 4.92e-32: 121: 20.53		YES_HUMAN (1-537): 0: 591: 71.61
+	Hs
		234882 SNX3_HUMAN (1-162): 5.77e-58: 179: 100.00		ABL1_HUMAN (42-537): 7.36e-167: 504: 39.56
+	Hs
		337593 SNX12_HUMAN (5-161): 8.43e-52: 164: 80.26		ABL1_HUMAN (42-537): 7.36e-167: 504: 39.56
+	Hs
		411888 SNX6_HUMAN (1-148): 1.05e-30: 116: 19.43		LCK_HUMAN (40-535): 0: 551: 57.60
+	Hs
		434102 SNX9_HUMAN (1-145): 4.92e-32: 121: 20.53		LYN_HUMAN (1-535): 0: 535: 54.48
+	Hs
		789017 SNX9_HUMAN (1-145): 4.92e-32: 121: 20.53		TEC_HUMAN (5-529): 6.12e-163: 478: 34.89